USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P28065 USC-OGP 2-DE database:  P28065 P28065 General information about the entry View entry in simple text format Entry name PSB9_HUMAN Primary accession number P28065 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Proteasome subunit beta type-9; EC=3.4.25.1; AltName: Full=Low molecular mass protein 2; AltName: Full=Macropain chain 7; AltName: Full=Multicatalytic endopeptidase complex chain 7; AltName: Full=Proteasome chain 7; AltName: Full=Proteasome subunit beta-1i; AltName: Full=Really interesting new gene 12 protein; Flags: Precursor;. Gene name Name=PSMB9 Synonyms=LMP2, PSMB6i, RING12 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0214: pI=4.70; Mw=21495 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1305: pI=4.71; Mw=22379 Cross-references UniProtKB/Swiss-Prot P28065; PSB9_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PSB9_HUMAN Primary accession number P28065 Secondary accession number(s) B0V0T1 Q16523 Q5JNW4 Sequence was last modified on  October 1, 1993 (version 2) Annotations were last modified on  March 15, 2017 (version 192) Name and origin of the protein Description RecName: Full=Proteasome subunit beta type-9; EC=3.4.25.1; AltName: Full=Low molecular mass protein 2; AltName: Full=Macropain chain 7; AltName: Full=Multicatalytic endopeptidase complex chain 7; AltName: Full=Proteasome chain 7; AltName: Full=Proteasome subunit beta-1i; AltName: Full=Really interesting new gene 12 protein; Flags: Precursor; Gene name Name=PSMB9 Synonyms=LMP2, PSMB6i, RING12 Encoded on Name=PSMB9; Synonyms=LMP2, PSMB6i, RING12 Keywords Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Host-virus interaction; Hydrolase; Immunity; Nucleus; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease; Zymogen. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X66401; CAA47024.1; -; Genomic_DNA EMBL X62741; CAA44603.1; -; mRNA EMBL Z14977; CAA78700.1; -; Genomic_DNA EMBL X87344; CAA60784.1; -; Genomic_DNA EMBL U01025; AAC50154.1; -; mRNA EMBL S75169; AAC60646.1; -; mRNA EMBL CR541656; CAG46457.1; -; mRNA EMBL AL669918; CAI18141.1; -; Genomic_DNA EMBL AL935043; CAI18627.1; -; Genomic_DNA EMBL BX088556; CAM26264.1; -; Genomic_DNA EMBL BX927138; CAQ08450.1; -; Genomic_DNA EMBL CR762476; CAQ08497.1; -; Genomic_DNA EMBL CR933844; CAQ08907.1; -; Genomic_DNA EMBL CR753889; CAQ10289.1; -; Genomic_DNA EMBL CH471081; EAX03654.1; -; Genomic_DNA EMBL BC065513; AAH65513.1; -; mRNA CCDS CCDS4759.1; -. [P28065-1]; . PIR A55632; A55632; . PIR S27332; S27332; . RefSeq NP_002791.1; NM_002800.4. [P28065-1]; . UniGene Hs.654585; -; . ProteinModelPortal P28065; -; . SMR P28065; -; . BioGrid 111671; 72; . IntAct P28065; 14; . MINT MINT-2802096; -; . STRING 9606.ENSP00000363993; -; . BindingDB P28065; -; . ChEMBL CHEMBL1944495; -; . DrugBank DB08889; Carfilzomib; . MEROPS T01.013; -; . iPTMnet P28065; -; . PhosphoSitePlus P28065; -; . BioMuta PSMB9; -; . DMDM 417529; -; . OGP P28065; -; . EPD P28065; -; . PaxDb P28065; -; . PeptideAtlas P28065; -; . PRIDE P28065; -; . DNASU 5698; -; . Ensembl ENST00000374859; ENSP00000363993; ENSG00000240065. [P28065-1]; . Ensembl ENST00000383114; ENSP00000372595; ENSG00000240118. [P28065-1]; . Ensembl ENST00000383234; ENSP00000372721; ENSG00000243594. [P28065-1]; . Ensembl ENST00000422729; ENSP00000407233; ENSG00000243067. [P28065-1]; . Ensembl ENST00000427870; ENSP00000412027; ENSG00000242711; . Ensembl ENST00000434471; ENSP00000393744; ENSG00000243958; . Ensembl ENST00000444284; ENSP00000396813; ENSG00000239836. [P28065-1]; . Ensembl ENST00000453059; ENSP00000407810; ENSG00000240508; . GeneID 5698; -; . KEGG hsa:5698; -; . UCSC uc003sga.4; human. [P28065-1]; . CTD 5698; -; . DisGeNET 5698; -; . GeneCards PSMB9; -; . H-InvDB HIX0166929; -; . H-InvDB HIX0207611; -; . H-InvDB HIX0207787; -; . HGNC HGNC:9546; PSMB9; . HPA CAB015180; -; . HPA HPA042818; -; . HPA HPA053280; -; . MIM 177045; gene; . neXtProt NX_P28065; -; . OpenTargets ENSG00000240065; -; . PharmGKB PA33891; -; . eggNOG KOG0174; Eukaryota; . eggNOG ENOG410XS23; LUCA; . GeneTree ENSGT00510000046484; -; . HOGENOM HOG000091079; -; . HOVERGEN HBG000123; -; . InParanoid P28065; -; . KO K02741; -; . OMA QVYGTMG; -; . OrthoDB EOG091G0GUI; -; . PhylomeDB P28065; -; . TreeFam TF106221; -; . Reactome R-HSA-1169091; Activation of NF-kappaB in B cells; . Reactome R-HSA-1234176; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; . Reactome R-HSA-1236974; ER-Phagosome pathway; . Reactome R-HSA-1236978; Cross-presentation of soluble exogenous antigens (endosomes); . Reactome R-HSA-174084; Autodegradation of Cdh1 by Cdh1:APC/C; . Reactome R-HSA-174113; SCF-beta-TrCP mediated degradation of Emi1; . Reactome R-HSA-174154; APC/C:Cdc20 mediated degradation of Securin; . Reactome R-HSA-174178; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; . Reactome R-HSA-174184; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; . Reactome R-HSA-180534; Vpu mediated degradation of CD4; . Reactome R-HSA-180585; Vif-mediated degradation of APOBEC3G; . Reactome R-HSA-187577; SCF(Skp2)-mediated degradation of p27/p21; . Reactome R-HSA-195253; Degradation of beta-catenin by the destruction complex; . Reactome R-HSA-202424; Downstream TCR signaling; . Reactome R-HSA-211733; Regulation of activated PAK-2p34 by proteasome mediated degradation; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2871837; FCERI mediated NF-kB activation; . Reactome R-HSA-349425; Autodegradation of the E3 ubiquitin ligase COP1; . Reactome R-HSA-350562; Regulation of ornithine decarboxylase (ODC); . Reactome R-HSA-382556; ABC-family proteins mediated transport; . Reactome R-HSA-450408; AUF1 (hnRNP D0) binds and destabilizes mRNA; . Reactome R-HSA-4608870; Asymmetric localization of PCP proteins; . Reactome R-HSA-4641257; Degradation of AXIN; . Reactome R-HSA-4641258; Degradation of DVL; . Reactome R-HSA-5358346; Hedgehog ligand biogenesis; . Reactome R-HSA-5362768; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; . Reactome R-HSA-5607761; Dectin-1 mediated noncanonical NF-kB signaling; . Reactome R-HSA-5607764; CLEC7A (Dectin-1) signaling; . Reactome R-HSA-5610780; Degradation of GLI1 by the proteasome; . Reactome R-HSA-5610783; Degradation of GLI2 by the proteasome; . Reactome R-HSA-5610785; GLI3 is processed to GLI3R by the proteasome; . Reactome R-HSA-5632684; Hedgehog 'on' state; . Reactome R-HSA-5658442; Regulation of RAS by GAPs; . Reactome R-HSA-5668541; TNFR2 non-canonical NF-kB pathway; . Reactome R-HSA-5676590; NIK-->noncanonical NF-kB signaling; . Reactome R-HSA-5678895; Defective CFTR causes cystic fibrosis; . Reactome R-HSA-5687128; MAPK6/MAPK4 signaling; . Reactome R-HSA-5689603; UCH proteinases; . Reactome R-HSA-5689880; Ub-specific processing proteases; . Reactome R-HSA-68827; CDT1 association with the CDC6:ORC:origin complex; . Reactome R-HSA-68949; Orc1 removal from chromatin; . Reactome R-HSA-69017; CDK-mediated phosphorylation and removal of Cdc6; . Reactome R-HSA-69229; Ubiquitin-dependent degradation of Cyclin D1; . Reactome R-HSA-69481; G2/M Checkpoints; . Reactome R-HSA-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; . Reactome R-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint; . Reactome R-HSA-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; . Reactome R-HSA-983168; Antigen processing: Ubiquitination & Proteasome degradation; . GeneWiki PSMB9; -; . GenomeRNAi 5698; -; . PRO PR:P28065; -; . Proteomes UP000005640; Chromosome 6; . Bgee ENSG00000239836; -; . CleanEx HS_PSMB9; -; . ExpressionAtlas P28065; baseline and differential; . Genevisible P28065; HS; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0000502; C:proteasome complex; TAS:ProtInc; . GO GO:0005839; C:proteasome core complex; ISS:UniProtKB; . GO GO:1990111; C:spermatoproteasome complex; ISS:UniProtKB; . GO GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW; . GO GO:0031145; P:anaphase-promoting complex-dependent catabolic process; TAS:Reactome; . GO GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAP-dependent; TAS:Reactome GO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome; . GO GO:0000165; P:MAPK cascade; TAS:Reactome; . GO GO:0090090; P:negative regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; TAS:Reactome; . GO GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; . GO GO:0038061; P:NIK/NF-kappaB signaling; TAS:Reactome; . GO GO:0090263; P:positive regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; TAS:Reactome; . GO GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0016579; P:protein deubiquitination; TAS:Reactome; . GO GO:0000209; P:protein polyubiquitination; TAS:Reactome; . GO GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome; . GO GO:2000116; P:regulation of cysteine-type endopeptidase activity; IMP:UniProtKB; . GO GO:0043488; P:regulation of mRNA stability; TAS:Reactome; . GO GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome; . GO GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0002223; P:stimulatory C-type lectin receptor signaling pathway; TAS:Reactome; . GO GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome; . GO GO:0055085; P:transmembrane transport; TAS:Reactome; . GO GO:0033209; P:tumor necrosis factor-mediated signaling pathway; TAS:Reactome; . GO GO:0016032; P:viral process; IEA:UniProtKB-KW; . GO GO:0060071; P:Wnt signaling pathway; planar cell polarity pathway; TAS:Reactome Gene3D 3.60.20.10; -; 1; . InterPro IPR029055; Ntn_hydrolases_N; . InterPro IPR000243; Pept_T1A_subB; . InterPro IPR016050; Proteasome_bsu_CS; . InterPro IPR001353; Proteasome_sua/b; . InterPro IPR023333; Proteasome_suB-type; . Pfam PF00227; Proteasome; 1; . PRINTS PR00141; PROTEASOME; . SUPFAM SSF56235; SSF56235; 1; . PROSITE PS00854; PROTEASOME_BETA_1; 1; . PROSITE PS51476; PROTEASOME_BETA_2; 1; .

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